Along with Ashok Krishnamurthy of RENCI (co-PI) and Guorong Wu of the BRIC (co-PI), we were funded for our proposal to develop a unified computational framework for analysis, storage, and visualization of 3D brain microscopy data from the NSF.
We welcome Oleh Krupa, a graduate student in the Joint Department of Biomedical Engineering at UNC - Chapel Hill and NC State, program to the lab!
We welcome Dan Liang, a graduate student in the Bioinformatics and Computational Biology program to the lab!
We published a review in Nature Medicine on autism genetics and neurobiology. We present on what we view as the current state of the field, showing that there is much genetic variation creating risk for autism yet to be discovered. We also detail some of the neurobiological hypotheses that have been put forward based on the genetic findings. Finally, we talk about the model systems used to study autism and their results as well as limitations.
Angela Elwell will begin as our lab manager/research specialist starting April 11th. Welcome Angela!
We published a paper in Nature Neuroscience about whether genetic variants which affect subcortical brain structure also affect risk for schizophrenia. Despite known volumetric differences in these structure in patients versus controls we find surprisingly little genetic overlap. A detailed description of the findings of this paper and their implications can be found in this video.